解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:To evaluate the highly active antiretroviral therapy (HAART) in the Kaposi's sarcoma evolution. PATIENTS AND METHOD:Retrospective analysis of a cohort of 126 HIV infected patients suffering from Kaposi's sarcoma with or without HAART. Clinical evolution, immunological status (CD4+ cell count) and response t...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71677-0
更新日期:2000-12-02 00:00:00
abstract:BACKGROUND:The poor phenotype/genotype correlation in Gaucher's disease makes difficult therapy-decision-making and prevention of complications. Gaucher's cells and tissue fibrosis are the earliest findings of the disease. Transforming growth factor ss (TGF-beta1) is the key cytokine involved in the regulation of tissu...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71637-x
更新日期:2000-11-11 00:00:00
abstract:BACKGROUND:There is poor information for isolated clinical tachycardia (ICT), that is to say, office tachycardia but normal ambulatory heart rate (HR). Our objective was to describe it and to know differences between hypertensive subjects with and without ICT. PATIENTS AND METHOD:Comparative study after a diagnostic i...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71627-7
更新日期:2000-11-04 00:00:00
abstract:BACKGROUND:We have examined the variation in the promoter region in the gene encoding UGT-1, associated with Gilbert's syndrome, in Spanish population. PATIENTS AND METHOD:Blood DNA was obtained from 100 blood donors. Polymerase chain reaction (PCR) was used to examine the A(TA)nTAA motif in the promoter region of the...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-10-28 00:00:00
abstract:BACKGROUND:In order to plan the objectives of the rehabilitation treatment after a stroke, it is necessary to know the functional prognosis of the patient. The main prognostic factors of disability in the hemiplegic patient, by means of an analysis of his neurological deficits (aphasia, disorientation, urinary incontin...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71602-2
更新日期:2000-10-21 00:00:00
abstract:BACKGROUND:To review the clinical findings of pancreatic tuberculosis and to establish a differential diagnosis with pancreatic tumours. PATIENTS AND METHODS:To describe three cases of pancreatic tuberculosis diagnosed in a 850 bed teaching hospital during the last two years. RESULTS:In the three case the imaging pro...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/s0025-7753(00)71592-2
更新日期:2000-10-14 00:00:00
abstract:UNLABELLED:Most experts, specially from Anglo-Saxon countries, recommend a low fat diet in order to prevent cardiovascular diseases. However, mortality rate by ischemic cardiopathy is low in Mediterranean countries, probably because of the consumption of a Mediterranean diet, with a high level of monounsaturated fats p...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71561-2
更新日期:2000-09-30 00:00:00
abstract:OBJECTIVE:To assess the compliance, tolerance and efficacy of a short chemoprophylaxis regimen (IR) for tuberculosis using isoniazid (INH) plus rifampin (RIF) during 3 months versus a standard regimen (I) of isoniazid during 12 months in HIV positive patients. MATERIAL AND METHODS:Prospective, comparative, randomized ...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0025-7753(00)71496-5
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The identification of high risk groups for genital human papillomavirus (HPV) infection may contribute to cervical cancer prevention. The study was designed to estimate the prevalence of HPV infection and the related risk of cervical cancer among imprisoned women. PATIENTS AND METHODS:157 women were visited...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71472-2
更新日期:2000-06-17 00:00:00
abstract:BACKGROUND:To study the evolution of the diet and the nutritional intake between 1983 and 1999, by age and sex. SUBJECTS AND METHODS:We performed a series of analysis of the food intake on a representative sample of the population of Reus (aged 10-69 years). Dietary intake was estimated using the 24-hours recall metho...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71448-5
更新日期:2000-06-03 00:00:00
abstract:BACKGROUND:A high prevalence of osteoporosis has been described in patients before and after cardiac transplantation. But clinical factors involved in previous bone loss in this condition are not well known. The purpose has been to study bone mineral density (BMD) in patients subject to cardiac transplantation, analyzi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71430-8
更新日期:2000-05-27 00:00:00
abstract:BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71331-5
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:A low folic acid (FA) intake may increase the risk of neural tube defects (NTD). We estimated the proportion of women with a FA intake < 400 micrograms/day, at the Valencian Region, exploring those factors associated with a FA intake < 400 micrograms/day. SUBJECTS AND METHOD:Daily FA intake was estimated fo...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71316-9
更新日期:2000-03-25 00:00:00
abstract:BACKGROUND:Advanced atrioventricular block (AB) during acute myocardial infarction (AMI), characterizes a high-risk subgroup of patients. Our aim was to determine the prognostic significance of AB and its possible peculiarities in relation to infarction localization and/or the thrombolytic therapy. PATIENTS AND METHOD...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71282-6
更新日期:2000-03-11 00:00:00
abstract:OBJECTIVES:To analyze the results, efficacy and safety of unilateral microelectrode guided pallidotomy for the treatment of advanced Parkinson's disease, three months and one year after surgery. PATIENTS AND METHODS:23 patients with advanced Parkinson's disease (mean age 58.9 years and mean disease duration 14.4 years...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-02-19 00:00:00
abstract:BACKGROUND:To determine the risk factors for the development of atopy in Spanish young adults. SUBJECTS AND METHODS:Case-control study over prevalent cases. Carried out in general population between the ages of 20 to 44 years old. Spanish participants of the ECRHS, a random representative sample of Spanish young adult...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71231-0
更新日期:2000-02-12 00:00:00
abstract:BACKGROUND:Exercise tests has been used in the diagnosis of metabolic myopathies. If there is an abnormal response pattern in mild mitochondrial myopathy (MM) and her role in the initial suspect diagnostic is unknown. SUBJECTS AND METHODS:Prospective study of 26 patients with mitochondrial myopathy (15 men, 11 women) ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71216-4
更新日期:2000-02-05 00:00:00
abstract:BACKGROUND:To identify and to compare the recommendations of the currently existing clinical protocols for arterial hypertension (HT) screening, diagnosis and baseline study in the Murcia Region, Spain, in order to assess their validity and reliability. MATERIAL AND METHODS:Structured comparative description of guidel...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The handling of upper gastrointestinal hemorrhage (UGH) usually includes the hospitalization of all patients, regardless of severity and prognosis. The aim of this paper is to assess the security of the outpatient control of some UGH, after their assessment in the hospital emergency room. PATIENTS AND METHO...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::The measurement of health-related quality of life (HRQOL) plays a very important role in the study of health outcomes, particularly in effectiveness studies. Nevertheless, the nature of these studies implies a series of challenges in the use of HRQOL instruments, due to the type of comparisons made, the heterogeneity ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:To assess how patients with diabetes experience their condition. PATIENTS AND METHOD:Pilot study conducted in 10 selected patients with type 1 diabetes. A structured interview guide was prepared including physical, social and emotional areas. The information provided was analyzed qualitatively, key statemen...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:In the present study we evaluated the influence of the observer's status--physician or nurse--on blood pressure levels and the relationship among clinic blood pressure measurement with ambulatory blood pressure and left ventricle mass. PATIENTS AND METHODS:Cross sectional study performed in seven primary ca...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-12-11 00:00:00
abstract:BACKGROUND:The annual consumption and costs of the health care resources used by ambulatory Alzheimer's disease patients were estimated. Patients were classified according to the degree of severity of the disease using Folstein's Mini Mental State Examination scale. The sociodemographic characteristics of both patients...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-11-27 00:00:00
abstract:OBJECTIVES:To assess the immunological and virological markers as potential predictors of progression to death in HIV-1 infected < 12 months of age. PATIENTS AND METHODS:Forty-three HIV-1 infants < 12 months of age were evaluated. None of the children received antiviral treatment, neither their mothers during pregnanc...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-11-06 00:00:00
abstract:BACKGROUND:"Stroke Code" is a system for the rapid identification, pre-notification and transport of acute ischemic stroke patients. The objective of this study was to evaluate the impact of delay reduction for thrombolytic therapy in these patients. SUBJECTS AND METHODS:We evaluated acute ischemic stroke patients adm...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-10-23 00:00:00
abstract:BACKGROUND:To examine whether provincial mortality from ischaemic heart disease and cerebrovascular disease in Spain in 1991-1995 is associated with infant mortality in 1930-1934, independently of illiteracy (an estimator of socioeconomic status) in 1991. MATERIAL AND METHODS:Population-correlation study. RESULTS:Inf...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-10-16 00:00:00
abstract:BACKGROUND:It has been previously reported that an exaggerated response of blood pressure to mental stress tasks is associated to an increased cardiovascular risk. The objective of this cross-sectional study, with sequential inclusion of subjects who met the inclusion criteria, was to asses the relationships between th...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-10-09 00:00:00
abstract:BACKGROUND:Bone mineral density (BMD) has been related with age, hormonal status, body mass index (BMI) and life style. We have evaluated the influence of these factors on BMD in healthy women, without risk factors for osteoporosis, using ultrasound measures. PATIENTS AND METHODS:We have selected 255 women (136 premen...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-09-18 00:00:00
abstract:BACKGROUND:Reimplantation disease (RD) is a postoperative complication in lung transplantation. It is defined as hypoxemia (PaO2/FiO2 ratio < 150 mmHg), radiologic infiltrates and decrease of lung compliance. The aim of the study was to analyze the incidence, predictive factors, prognosis and outcome of the patients wi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-06-26 00:00:00
abstract:BACKGROUND:Sentinel-node biopsy is meant to excise the first-echelon node from a primary tumor, which is the one that most probably harbors early metastases. PATIENTS AND METHODS:We report our results in 35 patients with breast cancer, using a radiotracer by peri-tumoral injection, pre-surgical scintigraphy and intrao...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-06-19 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV) increases the risk for anal premalignant lesions associated to human papillomavirus infection (HPV). The aim of this study was to compare the prevalence of HPV and squamous intraepithelial lesions (SIL) in patients with anal warts, with and without anti-HIV antibodies. PAT...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-06-12 00:00:00
abstract:BACKGROUND:To determine the nonfulfillment of antiinfectious therapy in clinical practice. MATERIAL AND METHODS:Fulfillment was quantified by tablet counting (TC) in the homes of 366 patients undergoing antibiotic treatment and the motives and predictive factors were identified. RESULTS:Nonfulfillment was of 61% (95%...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:
更新日期:1999-05-29 00:00:00
abstract:BACKGROUND:To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD:36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including cl...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-05-22 00:00:00
abstract:BACKGROUND:The renin-angiotensin system (RAS) plays an important role in blood pressure (BP) regulation. A number of RAS polymorphisms have been linked to essential hypertension (EH), but there is uncertainty about this association in other studies. We examined whether the insertion/deletion (I/D) polymorphism of the a...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Determinants associated with risk behaviours are evaluated in a known HIV-infected population not belonging to the great metropolitan nuclei. PATIENTS AND METHODS:110 unselected HIV+ patients were interviewed, including 77 variables. Their association with sharing needles, and unprotected sex is analysed. ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-04-24 00:00:00
abstract:BACKGROUND:To identify which clinical factors can modify the probability of the appearance of the psychotic syndromes in patients with idiopathic Parkinson's disease treated with levodopa. PATIENTS AND METHODS:214 patients were retrospectively studied to evaluate the appearance of hallucinosis, delusions or mental con...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-02-27 00:00:00
abstract:BACKGROUND:Asthma is one of the more prevalent diseases in childhood. Geographical differences have been found but it is unknown if they are true or are a consequence of the different methods used in the study of asthma. POPULATION AND METHODS:In 9 Spanish populations: Almería, Barcelona, Bilbao, Bahía de Cádiz, Carta...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:
更新日期:1999-02-13 00:00:00
abstract:BACKGROUND:To evaluate the fat consumption and main sources of specific fatty acids in adults from the south and north of Spain. SUBJECTS AND METHODS:Dietary data from 25,816 women and 15,635 men, aged 29-69 years, participants in the European Prospective Study on Cancer and Nutrition (EPIC) recruited in the north (As...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-02-06 00:00:00
abstract:BACKGROUND:A quantitative and qualitative assessment of reports on suspected adverse drug reactions (ARD) in Spanish medical literature was carried out. MATERIALS AND METHODS:The periods analysed were 1972-1974, 1986-1988 and 1992-1994, and the medical journals were Anales de Medicina Interna, Medicina Clínica and Rev...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-01-23 00:00:00
abstract::The main objective is to detail the main biases in the study of prognostic factors. Confounding bias is illustrated with social class, a prognostic factor still discussed. Within selection bias several cases are commented: response bias, specially frequent when the patients of a clinical trial are used; the shortcomin...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00